Bhardwaj lab is developing computational and experimental tools for high- throughput design of peptide-based therapeutics. We aim to develop a general rulebook of design principles for the custom design of peptides with enhanced membrane permeability, oral bioavailability, and blood-brain barrier traversal. We focus on designing peptides against a broad range of disease-related molecular targets, including validated targets in antibiotic resistance, chronic pain, and neurodegenerative disorders.
We are a member of the Department of Medicinal Chemistry, School of Pharmacy, and the Institute for Protein Design at the University of Washington, Seattle.
Research
Find out about our ongoing work on structure-guided design of peptides for intracellular targeting, oral bioavailability and blood-brain barrier traversal .
JOin US
We are a new lab focused on the interface of chemistry, biology and computational sciences. We are committed to maintaining healthy work-life balance and promoting diversity in sciences. Interested in joining our team? We are looking for undergraduate researchers, graduate students, postdoctoral fellows and research technicians.