SELECTED PUBLICATIONS
(1) Cyclic peptide structure prediction and design using AlphaFold [PDF]
Stephen A. Rettie, Katelyn V. Campbell, Asim K. Bera, Alex Kang, Simon Kozlov, Joshmyn De La Cruz, Victor Adebomi, Guangfeng Zhou, Frank DiMaio, Sergey Ovchinnikov†, Gaurav Bhardwaj† (2023) biorXiv (https://doi.org/10.1101/2023.02.25.529956) † co-corresponding authors
† co-corresponding authors
(2) Accurate de novo design of MEMBRANE TRAVERSING MACROCYCLES [PDF]
Bhardwaj G*†, O’Connor J*, Rettie S, Huang YH, Ramelot T, Mulligan V, Gokce G, Palmer J, Bera AK, Bick M, Piazza MD, Li X, Hosseinzadeh P, Craven T, Choi R, Tejero, R., Lauko, A., Glynn C, Dong, L., Griffin, R., van Voorhis W, Rodriguez J, Stewart L, Montelione GT, Craik D, Baker D† Cell 185 3520-3532 (2022)
*- equal contribution † co-corresponding authors
(3) Accurate de novo design of hyperstable constrained peptides [PDF]
Bhardwaj G*, Mulligan VK*, Bahl CD*, Gilmore JM, Harvey PJ, Cheneval O, Buchko GW, Pulavarti S, Kaas Q, Eletsky A, Huang P-S, Johnsen W, Greisen PJ, Rocklin GJ, Song Y, Linsky TW, Watkins AM, Rettie SR, Xu X, Carter LP, Bonneau R, Olson J, Coutsias E, Correnti CE, Szyperski T, Craik DJ and Baker D, Nature 538 (2016)
*- equal contribution
(4) Comprehensive computational design of ordered peptide macrocycles [PDF]
Hosseinzadeh P*, Bhardwaj G*, Mulligan VK*, Shortridge MD, Craven TW, Pardo-Avila F, Rettie SA, Kim DA, Silva D-A, Ibrahim YM, Webb IK, Cort JR, Adkins JA, Varani G, Baker D, Science, 358 (2017)
*- equal contribution
(5) Protection of the furin cleavage site in low-toxicity immunotoxins based on Pseudomonas Exotoxin A [PDF]
Kaplan G, Lee F, Onda M, Kolyvas E, Bhardwaj G, Baker D, Pastan I, Toxins 8 (8) (2016)
(6) A Novel Galectin-1 Inhibitor Discovered through One-Bead-Two-Compounds Library Potentiates the anti-tumor effects of Paclitaxel in vivo [PDF]
Shih T, Liu R, Fung G, Bhardwaj G, Ghosh P, Lam K, Molecular Cancer Therapeutics (2017)
(7) Covalent Chemical Ligation Strategy for Mono- and Polyclonal Immunoglobulins at Their Nucleotide Binding Sites [PDF]
Lac D, Feng C, Bhardwaj G, Le H, Tran J, Xing L, Fung G, Liu R, Cheng H, Lam KS, Bioconjugate Chemistry 27 (1) (2016)
(8) Targeting Btk/Etk of prostate cancer cells by a novel dual inhibitor [PDF]
Guo W, Liu R, Bhardwaj G, Yang JC, Changou C, Ma AH , Mazloom A, Chintapalli S, Xiao K, Xiao W, Kumaresan P, Sanchez E, Yeh CT, Evans CP, Patterson RL, Lam KS, Kung HJ, Cell death & disease, 5(9) (2015)
(9) PHYRN: A Robust Method for Phylogenetic Analysis of Highly Divergent Sequences [PDF]
Bhardwaj G, Ko K, Hong Y, Zhang Z, Chintapalli SV, Kline L, Gotlin M, Hartranft D, Patterson M, Dave F, Smith E, Holmes E, Patterson RL, van Rossum DB, PLoS One 7(4): e34261 (2012)